BLOG COMPARISONS

Blog Post1:
IKBKE gene amplification is seen loud and clear in breast cancer tumors!

Primary Article:
Boehm, Jesse S. et. al (2007). Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene. Cell Press Vol. 129, pp. 1065-1079

Blog Post 2:
Can we finally stop breast cancer from spreading?!

Primary Article:
Xiaoming Ju, Sanjay Katiyar, Chenguang Wang, Manran Liu, Xuanmao Jiao, Shengwen Li, Jie Zhou, Jacob Turner, Michael P. Lisanti, Robert G. Russell, Susette C. Mueller, John Ojeifo, William S. Chen, Nissim Hay, and Richard G. Pestell. (2007, May). Akt1 Governs Breast Cancer Progression In Vivo. Proceedings of the National Academy of Sciences, 104: 7438 – 7443.
Summary:
These two blog posts stood out to me the most because of the way they were so closely related. When I was reading the summaries it seemed as if the two articles could have both sited the other article as a secondary source. The first blog post talks about breast cancer and how the survival of breast cancer was due to the mutation of the gene IKBE. It describes the experiment that the researchers conducted to search the pathway of the IKBE gene and find out where the mutation occurs that leads to the vitality of breast cancer in general.
The second blog post talks about there ever being a cure for cancer. It mainly discussed the fact that researchers found that AKT1 which is involved in the pathway of IKBE was the key to finding a way to sustain breast cancer so that not as may women were dying from the disease. It also talks about how breast cancer is one of leading cancers in America which is also true. It was basically extremely interesting to me how the two articles went hand in hand with one another.

Questions:
1. Did these two articles ever site each other as sources?
2. What new research is being done in breast cancer research?
3. What is the connection between IKBE and AKT1?