Does the Estrogen Receptor βeta have an Influential Role in inhibiting the Effects of Ovarian Cancer?

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Does the Estrogen Receptor βeta have an Influential Role in inhibiting the Effects of Ovarian Cancer?
Early discoveries showed evidence of the estrogen hormone playing a role in cancer. Although researchers knew that estrogen has an effect on cancer their knowledge of its specific role was vague. Researchers limited knowledge and urge to learn more was what lead to further studies about estrogen. The reason why an estrogen ovarian cancer study was conducted is that ovarian cancer is very common amongst women and has a high mortality rate. Also, estrogen has a correlation with ovarian cancer and a study would determine the exact correlation between estrogen and ovarian cancer. The results of a successful study would lead to future drugs for treatment of ovarian cancer and other cancers.
The study was conducted with approximately four dozen test subjects. The subjects were women who had ovarian cancer. Ovarian cysts and tumors were extracted from the patients in order to be used as test material. Normal ovaries were used as the control. The cysts and tumors were tested to see if they showed signs of for ERα and or ERβ receptors. The researchers wanted to see if these two receptors of the same family had a different effect on cancer proliferation.
The tests on the cyst and tumors showed that both ERα and ERβ receptors were present in the infected cells. The ERβ receptors were depleted in number compared to the number of receptors present in a healthy individual. The roles of the receptors were also very much different in how the effected the progression of cancer. The ERα receptors had little effect on inhibiting cell growth. The ERβ receptors seem to have an inhibitory effect on cell growth and mobility.
Later in the study the normal ovaries were study in order to confirm the researchers’ suspicions. The normal ovaries were infected with various viruses that would make the normal ovaries become cancerous. After a 24hr span the ovaries were attempted to be treated by the researchers. The researchers introduced ERα and ERβ receptors to the infected cells. The ERα receptors did not have much of an inhibitory effect on cancer cell proliferation. On the other hand the ERβ receptors had a great inhibitory effect on the cancer cells proliferation and mobility. ERβ receptors slowed cell proliferation and mobility by over 50% which confirmed the researchers’ suspicions that ERβ receptors are inhibitors of cancer cells.
The two articles that I used to gather information on the studied topic were both beneficial. Both articles gave the same information. The only differences between the articles is that the secondary source was a condense version of the primary source; and that the primary source was just more in depth about numerical data and included charts. The overall content of both articles were the same in regards of being equally informative. I believe that the articles are a huge break through for future cancer treatment. Both articles are equally beneficial. Although, the primary source is more in depth with its data, the secondary source is easier to be understood by some one who does not have a strong science background.
Some additional questions are:
1.What are scientists going to do with this new found information?
2.Will more studies be conducted to see how ERβ receptors affect other types of cancers?